President Joe Biden hopes to focus on the flow of fentanyl into the United States during a Mexico City meeting with leaders from Mexico and Canada next week, National Security Council spokesman John Kirby told reporters in the White House on Friday.

Biden’s Mexico City agenda includes discussion of supply chains, fentanyl, climate change, immigration and drug cartels, Kirby said.

Asked about specific steps the United States would like to see Mexico take to stop the production and smuggling of fentanyl, Kirby said he didn’t want to get ahead of the summit. “They’re going to talk about a lot of this,” he said.

The recent arrest of cartel leader Ovidio Guzman “is not an insignificant accomplishment by Mexican authorities,” Kirby said. “It’s not like we haven’t had some success. I mean 20,000 pounds is a lot,” he said, referring to the amount of the drug U.S. customs authorities have seized since last August.

“But it just keeps coming,” Kirby said.